SCHEMBL5177828

SCHEMBL5177828

CCC(C)(CC)[N]CC(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.31
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270918 0.73
SCHEMBL1678183 0.69
SCHEMBL5933565 0.67 TSHR (0.30) TSHRTDP1
Isobutane SCHEMBL27848533 0.64 TSHR (0.73) TSHRTDP1
SCHEMBL185542 0.61 TSHR (0.43) TSHRTDP1
SCHEMBL1353673 0.61 TSHR (0.43) TSHRTDP1
SCHEMBL277066 0.61 TSHR (0.43) TSHRTDP1
Isobutane SCHEMBL15529098 0.59 TSHR (0.35) TSHRTDP1
SCHEMBL1678166 0.59
Isobutane SCHEMBL10581236 0.59 TSHR (0.40) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221436-B1 Process for the preparation of secondary amines from nitriles BASF AG (DE) 2007-04-18 EP disclosed
EP-1221437-B1 Process for the preparation of primary and secondary amines from nitriles BASF AG (DE) 2005-07-06 EP disclosed
EP-0869113-B1 Process for the preparation of tertiary amines fromnitriles and secondary amines BASF AG (DE) 2003-06-04 EP disclosed
EP-1221437-A1 Process for the preparation of primary and secondary amines from nitriles BASF AKTIENGESELLSCHAFT (DE) 2002-07-10 EP disclosed
EP-1221436-A2 Process for the preparation of secondary amines from nitriles BASF AKTIENGESELLSCHAFT (DE) 2002-07-10 EP disclosed
WO-1999032429-A2 METHOD FOR PRODUCING SECONDARY AMINES FROM NITRILES AND PRIMARY AMINES BASF AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed
EP-0869113-A2 Process for the preparation of tertiary amines fromnitriles and secondary amines BASF AKTIENGESELLSCHAFT (DE) 1998-10-07 EP disclosed