Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178740 | 0.94 | AOC3 (0.44) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4867212 | 0.88 | AOC3 (0.58) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL5547016 | 0.85 | AOC3 (0.55) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL5547043 | 0.85 | AOC3 (0.55) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL5551573 | 0.85 | AOC3 (0.56) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4887509 | 0.84 | AOC3 (0.53) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4870584 | 0.82 | AOC3 (0.58) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL5545486 | 0.82 | AOC3 (0.53) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4887312 | 0.79 | AOC3 (0.55) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4881038 | 0.79 | AOC3 (0.50) | AOC3MAOBSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791835-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006028269-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 IHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-03-16 | — | — | WO | disclosed |