Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | Q9HBH1 | 1/20 | 0.37 | |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205637 | 1.00 | PLA2G2C (0.44) | PLA2G2CPLA2G10GPR84ACE2PLA2G2A | |
| SCHEMBL4192229 | 0.98 | PLA2G2C (0.43) | PLA2G2CPLA2G10GPR84ACE2PLA2G2A | |
| Hydrochloric Acid SCHEMBL4199756 | 0.98 | PLA2G2C (0.43) | PLA2G2CPLA2G10GPR84ACE2PLA2G2A | |
| SCHEMBL4211648 | 0.90 | PLA2G10 (0.40) | PLA2G2CPLA2G10GPR84PLA2G2AALDH1A1 | |
| SCHEMBL6464991 | 0.84 | PLA2G2C (0.54) | PLA2G2CPLA2G10GPR84PLA2G2APDF | |
| SCHEMBL14090829 | 0.84 | PLA2G2C (0.54) | PLA2G2CPLA2G10GPR84PLA2G2APDF | |
| SCHEMBL7944471 | 0.84 | PLA2G2C (0.54) | PLA2G2CPLA2G10GPR84PLA2G2APDF | |
| SCHEMBL4192232 | 0.84 | CRAT (0.47) | PLA2G2C | |
| SCHEMBL4011955 | 0.83 | DPP7 (0.50) | PLA2G2CPLA2G10GPR84ACE2PDF | |
| SCHEMBL4007878 | 0.83 | DPP7 (0.50) | PLA2G2CPLA2G10GPR84ACE2PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768952-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Warner-Lambert Company LLC (US) | 2007-04-04 | — | — | EP | claimed |
| WO-2006008612-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | WARNER-LAMBERT COMPANY LLC (US) | 2006-01-26 | — | — | WO | claimed |