Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14281004 | 0.86 | AOC3 (0.61) | AOC3MAOBADRA2BSLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4888620 | 0.85 | AOC3 (0.60) | AOC3MAOBADRA2BSLC6A4SLC6A3 | |
| SCHEMBL4890441 | 0.81 | AOC3 (0.58) | AOC3MAOBADRA2BSLC6A4SLC6A3 | |
| SCHEMBL16653828 | 0.79 | MCHR1 (0.58) | MAOBMCHR1SIRT1 | |
| SCHEMBL14281006 | 0.78 | AOC3 (0.61) | AOC3MAOBADRA2BSLC6A4SLC6A3 | |
| SCHEMBL4880224 | 0.78 | AOC3 (0.63) | AOC3MAOB | |
| Hydrochloric Acid SCHEMBL4880230 | 0.77 | AOC3 (0.60) | AOC3MAOBADRA2BSLC6A4SLC6A3 | |
| SCHEMBL4885619 | 0.77 | AOC3 (0.61) | AOC3MAOB | |
| SCHEMBL4890223 | 0.76 | AOC3 (0.55) | AOC3MAOB | |
| SCHEMBL6387644 | 0.75 | AOC3 (0.72) | AOC3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791835-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006028269-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 IHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-03-16 | — | — | WO | disclosed |