Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL4890251 | 0.97 | AOC3 (0.56) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL14281008 | 0.84 | AOC3 (0.56) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL4883513 | 0.83 | AOC3 (0.55) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4890242 | 0.83 | AOC3 (0.52) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL16266006 | 0.80 | AOC3 (0.51) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL974214 | 0.79 | AOC3 (0.73) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL972138 | 0.79 | AOC3 (0.65) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL5201750 | 0.79 | AOC3 (0.53) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL972980 | 0.78 | AOC3 (0.57) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4886677 | 0.78 | AOC3 (0.57) | AOC3MAOBSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791835-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006028269-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 IHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-03-16 | — | — | WO | disclosed |