Azetidine

Azetidine

SCHEMBL517869

C1CNC1.[N]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azetidine SCHEMBL30933119 0.94
Azetidine SCHEMBL12502 0.93
Azetidine SCHEMBL28328821 0.93
Pyrrolidine SCHEMBL145389 0.88
Azetidine SCHEMBL23754598 0.86
Azetidine SCHEMBL8051426 0.86
Azetidine SCHEMBL17460187 0.86
Azetidine SCHEMBL5747121 0.86
Azetidine SCHEMBL2004110 0.86
Azetidine SCHEMBL8612367 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024025389-A1 METHOD FOR PREPARING INTERMEDIATE OF PHTHALAZINONE DERIVATIVE 아이디언스 주식회사 2024-02-01 WO claimed
EP-4139298-A1 PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF Idience Co., Ltd. (KR) 2023-03-01 EP claimed
CN-114206893-A (hetero) aryl-methyl-thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN claimed
CN-114206892-A (2-acetamido) thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN claimed
WO-2021214502-A1 PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF IDIENCE CO., LTD. (KR) 2021-10-28 WO claimed
US-20210323946-A1 PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF IDIENCE CO., LTD. (KR) 2021-10-21 US claimed
CN-1125064-C 3-pyridyl enantiomers and their use as analgesics ABBOTT LAB (US) 2003-10-22 CN claimed
EP-0871623-B1 3-AZETIDINYLALKYLPIPERIDINES OR -PYRROLIDINES AS TACHYKININ ANTAGONISTS PFIZER RES & DEV (IE) 2003-02-12 EP claimed
EP-0950057-B1 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS ABBOTT LAB (US) 2002-11-13 EP claimed
US-6242438-B1 3-Azetidinylalkylpiperidines or -pyrrolidines as tachykinin antagonists PFIZER INC. 2001-06-05 US claimed
CN-1245496-A 3-pyridyl enantiomers and their use as analgesics ABBOTT LAB (US) 2000-02-23 CN claimed
EP-0950057-A1 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS Abbott Laboratories (US) 1999-10-20 EP claimed
EP-0871623-A1 3-AZETIDINYLALKYLPIPERIDINES OR -PYRROLIDINES AS TACHYKININ ANTAGONISTS Pfizer Research and Development Company, N.V./S.A. (IE) 1998-10-21 EP claimed
WO-1998025920-A1 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS ABBOTT LABORATORIES (US) 1998-06-18 WO claimed
WO-1997025322-A1 3-AZETIDINYLALKYLPIPERIDINES OR -PYRROLIDINES AS TACHYKININ ANTAGONISTS PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) 1997-07-17 WO claimed
US-12583837-B2 Solid forms comprising (s)-2-(2,6-dioxopiperidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1,3-dione and salts thereof, and compositions comprising and methods of using the same CELGENE CORPORATION (US) 2026-03-24 US disclosed
EP-4630118-A1 CRYSTALLINE ADIPIC ACID SALT FORM OF A CCR6 ANTAGONIST Idorsia Pharmaceuticals Ltd (CH) 2025-10-15 EP disclosed
EP-0102740-A1 N-formyl and n-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides and their preparation and use A.H. ROBINS COMPANY, INCORPORATED (US) 1984-03-14 EP disclosed
EP-0102194-A1 3-Phenoxy-1-azetidinecarboxamides and their use and preparation A.H. ROBINS COMPANY, INCORPORATED (US) 1984-03-07 EP disclosed
US-4379151-A 3-Phenoxyazetidines for anorexigenic activity A. H. ROBINS COMPANY, INC. (US) 1983-04-05 US disclosed