⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048888 | 1.00 | — | — | |
| SCHEMBL696562 | 0.96 | CYP2B6 (0.32) | — | |
| Hydrochloric Acid SCHEMBL16238627 | 0.96 | — | — | |
| SCHEMBL5390320 | 0.96 | CYP2B6 (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL31168140 | 0.93 | CYP2B6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1507301 | 0.93 | CYP2B6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL9035395 | 0.93 | CYP2B6 (0.31) | — | |
| Bromide SCHEMBL29204968 | 0.93 | CYP2B6 (0.31) | — | |
| SCHEMBL3505975 | 0.92 | — | — | |
| SCHEMBL10006193 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227343-B2 | Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | VANDERBILT UNIVERSITY (US) | 2019-03-12 | — | — | US | claimed |
| US-10039782-B2 | Onychomycosis treatment apparatus and method | DEVICEFARM, INC. (US) | 2018-08-07 | — | — | US | claimed |
| US-10039723-B2 | Onychomycosis treatment system and method | DEVICEFARM, INC. (US) | 2018-08-07 | — | — | US | claimed |
| US-9890167-B2 | Pyrazine compounds for the treatment of infectious diseases | HOFFMANN-LA ROCHE INC. (US) | 2018-02-13 | — | — | US | claimed |
| US-20180022745-A1 | ISOQUINILINE AND NAPTHALENE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY | 2018-01-25 | — | — | US | claimed |
| US-20160237090-A1 | NOVEL PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 2016-08-18 | — | — | US | claimed |
| WO-2016115272-A1 | BENZOTHIAZOLE AND BENZISOTHIAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY (US) | 2016-07-21 | — | — | WO | claimed |
| EP-2855457-A1 | AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis Products LLC (US) | 2015-04-08 | — | — | EP | claimed |
| WO-2013169622-A1 | AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2013-11-14 | — | — | WO | claimed |
| CN-101519405-A | 8a-(trifluoro-methyl)hexahydro pyrrolo[1,2-a]pyrimidine-6(7H)-ketone and method for synthesizing same | UNIV SHANGHAI | 2009-09-02 | — | — | CN | claimed |
| EP-1028828-A2 | METHODS OF WORKING METAL AND COMPOSITIONS USEFUL AS WORKING FLUIDS THEREFOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-08-23 | — | — | EP | claimed |
| US-6043201-A | Composition for cutting and abrasive working of metal | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-28 | — | — | US | claimed |
| WO-1999025516-A2 | METHODS OF WORKING METAL AND COMPOSITIONS USEFUL AS WORKING FLUIDS THEREFOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-05-27 | — | — | WO | claimed |
| US-5839311-A | HYDROFLUOROETHERS; LUBRICATION, COOLING DURING METAL WORKING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-24 | — | — | US | claimed |
| CN-1190390-A | Nitric oxide synthase inhibitors derived from cyclic amidines | SEARLE & CO (US) | 1998-08-12 | — | — | CN | claimed |
| EP-0509739-B1 | Water displacement composition and a method of use | MINNESOTA MINING & MFG (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0509739-A2 | Water displacement composition and a method of use | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-21 | — | — | EP | claimed |
| US-5089152-A | Liquid perfluorinated chlorine-free inert solvent, soluble fluoroaliphatic nonionic surfactant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-02-18 | — | — | US | claimed |
| US-20260069571-A1 | DDR1 AND DDR2 INHIBITORS FOR THE TREATEMENT OF CANCER AND FIBROTIC DISEASES | REDX PHARMA PLC (GB) | 2026-03-12 | — | — | US | disclosed |
| US-5089152-A | Liquid perfluorinated chlorine-free inert solvent, soluble fluoroaliphatic nonionic surfactant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-02-18 | — | — | US | disclosed |