Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128528 | 0.99 | HTT (0.46) | PPARAHTTKAT8KDM4EALDH1A1 | |
| SCHEMBL5179731 | 0.94 | PPARA (0.48) | PPARAHTTKAT8KDM4EALDH1A1 | |
| SCHEMBL129098 | 0.94 | PPARA (0.48) | PPARAHTTKAT8KDM4EALDH1A1 | |
| SCHEMBL9342859 | 0.84 | PPARA (0.47) | PPARAHTTKAT8KDM4EALDH1A1 | |
| SCHEMBL2807990 | 0.84 | PDE5A (0.47) | PPARAALDH1A1RARB | |
| SCHEMBL9342860 | 0.84 | PPARA (0.47) | PPARAHTTKAT8KDM4EALDH1A1 | |
| SCHEMBL9746372 | 0.84 | PPARA (0.47) | PPARAHTTKAT8KDM4EALDH1A1 | |
| SCHEMBL8364755 | 0.84 | ACE2 (0.44) | PPARATSHRRARB | |
| SCHEMBL6871353 | 0.84 | PPARA (0.47) | PPARAHTTKAT8KDM4EALDH1A1 | |
| SCHEMBL30522481 | 0.83 | POLB (0.45) | PPARAKAT8KDM4EALDH1A1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1596113-B1 | Thermoplastic polyamide moulding matters | EMS CHEMIE AG (CH) | 2007-06-13 | — | — | EP | disclosed |
| US-7151127-B2 | Use of thermoplastic polyamide molding compositions with reduced formation of solid deposits and/or coverings | EMS-CHEMIE AG (CH) | 2006-12-19 | — | — | US | disclosed |
| US-20050148728-A1 | Use of thermoplastic polyamide moulding compositions with reduced formation of solid deposits and/or coverings | EMS-CHEMIE AG (CH) | 2005-07-07 | — | — | US | disclosed |
| EP-1550684-A2 | Use of thermoplastic polyamide moulding compositions showing reduced formation of solid deposits | EMS-Chemie AG (CH) | 2005-07-06 | — | — | EP | disclosed |