Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5276228 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL5279658 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL12917491 | 0.91 | KDM4E (0.55) | KDM4EALDH1A1TDP1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL968783 | 0.91 | KDM4E (0.54) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL5180014 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL5242516 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL5280703 | 0.85 | KCNH2 (0.47) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL5178558 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL5279142 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL12917464 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1TDP1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768973-A1 | SUBSTITUTED QUINOLONES | AiCuris GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008046-A1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO. KG (DE) | 2006-01-26 | — | — | WO | disclosed |