Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A3 | Q9HAS3 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181210 | 1.00 | SLC28A3 (0.55) | SLC28A3TDP1POLBXDHPTPN1 | |
| SCHEMBL4371490 | 0.97 | SLC28A3 (0.55) | SLC28A3TDP1POLBXDHPTPN1 | |
| SCHEMBL4366964 | 0.97 | SLC28A3 (0.55) | SLC28A3TDP1POLBXDHPTPN1 | |
| SCHEMBL5193197 | 0.91 | TDP1 (0.55) | SLC28A3TDP1POLBXDHCA12 | |
| SCHEMBL5180485 | 0.90 | ESR1 (0.50) | SLC28A3TDP1XDHPTPN1ESR1 | |
| SCHEMBL4368198 | 0.87 | SLC28A3 (0.54) | SLC28A3TDP1POLBXDH | |
| SCHEMBL4368675 | 0.87 | SLC28A3 (0.54) | SLC28A3TDP1POLBXDH | |
| SCHEMBL5181117 | 0.86 | SLC28A3 (0.56) | SLC28A3TDP1 | |
| SCHEMBL4378546 | 0.82 | SLC28A3 (0.56) | SLC28A3POLB | |
| SCHEMBL13576873 | 0.82 | USP2 (0.60) | SLC28A3TDP1PTPN1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282520-B2 | External preparation | LION CORPORATION (JP) | 2007-10-16 | — | — | US | disclosed |
| EP-1437119-B1 | EXTERNAL PREPARATION CONTAIINING GALLIC ACID DERIVATIVES | LION CORP (JP) | 2007-08-15 | — | — | EP | disclosed |
| CN-1250194-C | External preparation | LION CORP (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1568173-A | External preparation | LION CORP (JP) | 2005-01-19 | — | — | CN | disclosed |
| EP-1437119-A1 | EXTERNAL PREPARATION | Lion Corporation (JP) | 2004-07-14 | — | — | EP | disclosed |