SCHEMBL5181128

SCHEMBL5181128

CCCCN1/C(=C\C=C2\CCCC(/C=C/C3=[N+](CCCC)c4ccccc4C3(C)C)=C2Cl)C(C)(C)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 6/20 0.53
PRMT5 O14744 1/20 0.47
CARM1 Q86X55 1/20 0.47
PRMT8 Q9NR22 1/20 0.47
APP P05067 2/20 0.46
MAPT P10636 3/20 0.45
MEN1 O00255 2/20 0.45
HTT P42858 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
USP2 O75604 1/20 0.45
S1PR2 O95136 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
ALPG P10696 1/20 0.45
THRB P10828 1/20 0.45
PKM P14618 1/20 0.45
XBP1 P17861 1/20 0.45
CRHBP P24387 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12364494 1.00 PRMT1 (0.53) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL5181135 1.00 PRMT1 (0.53) PRMT1PRMT5CARM1PRMT8APP
Iodide SCHEMBL30976557 0.99 PRMT1 (0.53) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL19470194 0.97 PRMT1 (0.51) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL19470193 0.97 PRMT1 (0.51) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL12713683 0.96 PRMT1 (0.53) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL16609257 0.96 PRMT1 (0.54) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL14597383 0.95 PRMT1 (0.52) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL31673509 0.95 PRMT1 (0.52) PRMT1PRMT5CARM1PRMT8APP
SCHEMBL13898147 0.95 PRMT1 (0.52) PRMT1PRMT5CARM1PRMT8APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1655317-B1 Thermally reactive infrared absorption polymers and their use in a heat sensitive lithographic printing plate IPAGSA IND SL (ES) 2007-06-13 EP claimed
EP-3207360-A1 ANALYTICAL METHOD USING SURFACE ENHANCED RAMAN SPECTROSCOPY AND COMPOSITION FOR THE METHOD Johnson Matthey Public Limited Company (GB) 2017-08-23 EP disclosed
WO-2016059429-A1 ANALYTICAL METHOD USING SURFACE ENHANCED RAMAN SPECTROSCOPY AND COMPOSITION FOR THE METHOD JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2016-04-21 WO disclosed