SCHEMBL5181431

SCHEMBL5181431

O=C(O)c1cc(O)c(OC2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 4/20 0.58
HKDC1 Q2TB90 3/20 0.58
L3MBTL1 Q9Y468 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
TNNI3 P19429 2/20 0.58
TNNT2 P45379 2/20 0.58
TNNC1 P63316 2/20 0.58
KDM4E B2RXH2 2/20 0.58
MEN1 O00255 2/20 0.58
CYP3A4 P08684 2/20 0.58
MAPT P10636 2/20 0.58
MAPK1 P28482 2/20 0.58
RECQL P46063 2/20 0.58
KMT2A Q03164 2/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
LMNA P02545 1/20 0.58
GLA P06280 1/20 0.58
THRB P10828 1/20 0.58
HPGD P15428 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3140292 1.00 USP2 (0.58) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL13576893 1.00 USP2 (0.58) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL13577089 1.00 USP2 (0.58) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL5181145 1.00 USP2 (0.58) USP2HKDC1L3MBTL1TDP1TNNI3
Ammonia Solution, Strong SCHEMBL5181807 0.99 USP2 (0.57) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL5180928 0.94 USP2 (0.58) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL5181812 0.91 USP2 (0.60) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL13577086 0.91 USP2 (0.60) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL3232003 0.91 USP2 (0.60) USP2HKDC1L3MBTL1TDP1TNNI3
SCHEMBL13576873 0.91 USP2 (0.60) USP2HKDC1L3MBTL1TDP1TNNI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337162-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC Management LLC (US) 2024-03-20 EP claimed
CN-117545458-A Hair bleaching compositions and methods of use thereof ELC管理有限责任公司 2024-02-09 CN claimed
US-20220362124-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MAN LLC (US) 2022-11-17 US claimed
WO-2022241166-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MANAGEMENT LLC (US) 2022-11-17 WO claimed
US-11298308-B1 Hair bleaching compositions and methods of use ELC MANAGEMENT LLC (US) 2022-04-12 US claimed
EP-4337162-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC Management LLC (US) 2024-03-20 EP disclosed
CN-117545458-A Hair bleaching compositions and methods of use thereof ELC管理有限责任公司 2024-02-09 CN disclosed
US-11602497-B2 Hair bleaching compositions and methods of use ELC MANAGEMENT LLC (US) 2023-03-14 US disclosed
WO-2022241166-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MANAGEMENT LLC (US) 2022-11-17 WO disclosed
US-20220362124-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MAN LLC (US) 2022-11-17 US disclosed
US-11298308-B1 Hair bleaching compositions and methods of use ELC MANAGEMENT LLC (US) 2022-04-12 US disclosed
US-7282520-B2 External preparation LION CORPORATION (JP) 2007-10-16 US disclosed
EP-1437119-B1 EXTERNAL PREPARATION CONTAIINING GALLIC ACID DERIVATIVES LION CORP (JP) 2007-08-15 EP disclosed
CN-1250194-C External preparation LION CORP (JP) 2006-04-12 CN disclosed
CN-1568173-A External preparation LION CORP (JP) 2005-01-19 CN disclosed
US-20040247551-A1 External preparation LION CORPORATION (JP) 2004-12-09 US disclosed
EP-1437119-A1 EXTERNAL PREPARATION Lion Corporation (JP) 2004-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220362124-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE CAT, TYR, GPX1 USP2 1228/4885HKDC1 871/4885L3MBTL1 2790/4885
US-20040247551-A1 External preparation GANAB, GANC, EEA1 USP2 2373/4885HKDC1 953/4885L3MBTL1 4118/4885
US-11602497-B2 Hair bleaching compositions and methods of use CAT, TYR, GPX1 USP2 1228/4885HKDC1 871/4885L3MBTL1 2790/4885
US-11298308-B1 Hair bleaching compositions and methods of use CAT, TYR, GPX1 USP2 1228/4885HKDC1 871/4885L3MBTL1 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.