Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.62 |
| ▸ | CNR1 | P21554 | 6/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181277 | 0.96 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL5181212 | 0.96 | CNR2 (0.61) | CNR2CNR1KCNH2 | |
| SCHEMBL5179673 | 0.95 | CNR2 (0.60) | CNR2CNR1KCNH2 | |
| SCHEMBL5181581 | 0.93 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL5182040 | 0.93 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL5179925 | 0.93 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL5181672 | 0.93 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL5181670 | 0.91 | CNR2 (0.56) | CNR2CNR1KCNH2 | |
| SCHEMBL5181950 | 0.89 | CNR2 (0.56) | CNR2CNR1KCNH2 | |
| SCHEMBL5181403 | 0.89 | CNR2 (0.56) | CNR2CNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797070-A1 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATIONS THEREOF AND USES THEREOF II | AstraZeneca AB (SE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006033633-A1 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATIONS THEREOF AND USES THEREOF II | ASTRAZENECA AB (SE) | 2006-03-30 | — | — | WO | disclosed |