Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027602 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3031517 | 0.94 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3027056 | 0.93 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3023069 | 0.92 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3128730 | 0.91 | ABCB1 (0.44) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3021052 | 0.89 | HIF1A (0.51) | MAPTNPC1KDM4ERAB9ALMNA | |
| SCHEMBL3027608 | 0.88 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3031690 | 0.88 | MAPT (0.49) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3026410 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3027592 | 0.85 | MEN1 (0.48) | SMN1; SMN2MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |