Ethane

Ethane

SCHEMBL5184530

CC.Cl[Ni]Cl.c1ccc(Pc2ccccc2)cc1.c1ccc(Pc2ccccc2)cc1

nearest known ligand 0.33

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33
TSHR P16473 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GLA P06280 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA9 Q16790 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL679059 1.00 ELANE (0.33) ELANETSHRCA12CA1CA2
SCHEMBL28278593 0.94 TSHR (0.35) TSHRCA12CA1CA2GLA
SCHEMBL28905535 0.94 TSHR (0.35) TSHRCA12CA1CA2GLA
Propane SCHEMBL678752 0.90 TP53 (0.36) ELANELMNANPSR1
Propane SCHEMBL1231243 0.90 TP53 (0.36) ELANELMNANPSR1
Ethane SCHEMBL2219423 0.88 TSHR (0.39) TSHRCA12CA1CA2GLA
Ethane SCHEMBL28807723 0.88 TSHR (0.39) TSHRCA12CA1CA2GLA
Ethane SCHEMBL372202 0.88 TSHR (0.39) TSHRCA12CA1CA2GLA
Butane SCHEMBL3766698 0.87 TP53 (0.35) ELANENPSR1
Ethane SCHEMBL28216822 0.85 TSHR (0.37) TSHRCA12CA1CA2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591128-B Direct cross-coupling method of aryl sulfide salt and aryl bromide 南京工业大学 2023-08-22 CN claimed
CN-109694350-B Compound containing fluoromethyl and preparation method thereof 中国科学院上海有机化学研究所 2023-05-09 CN claimed
CN-114591128-B Direct cross-coupling method of aryl sulfide salt and aryl bromide 南京工业大学 2023-08-22 CN disclosed
CN-109694350-B Compound containing fluoromethyl and preparation method thereof 中国科学院上海有机化学研究所 2023-05-09 CN disclosed
CN-109908954-A A kind of chiral aldehydes catalyst and preparation method and the method for being catalyzed asymmetric nucleophilic addition 西南大学 2019-06-21 CN disclosed
US-8318995-B2 Asymmetric pyrene derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
EP-1749809-A1 ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-02-07 EP disclosed