Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122210 | 0.82 | BRAF (0.78) | BRAF | |
| SCHEMBL1122847 | 0.75 | BRAF (0.55) | BRAF | |
| SCHEMBL5986841 | 0.73 | BRAF (0.54) | BRAFRAF1 | |
| SCHEMBL1122509 | 0.70 | BRAF (1.00) | BRAF | |
| SCHEMBL1122460 | 0.70 | BRAF (1.00) | BRAF | |
| SCHEMBL1122155 | 0.69 | BRAF (0.87) | BRAF | |
| SCHEMBL1122378 | 0.68 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL1122654 | 0.67 | BRAF (0.80) | BRAF | |
| SCHEMBL1122490 | 0.67 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL2330756 | 0.66 | TEAD4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831184-A2 | PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS | The Wellcome Trust Limited (GB) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006067466-A2 | PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS | THE WELLCOME TRUST LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |