⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15238190 | 0.86 | — | — | |
| SCHEMBL17970403 | 0.72 | — | — | |
| SCHEMBL4404074 | 0.67 | — | — | |
| SCHEMBL932700 | 0.67 | — | — | |
| SCHEMBL17935121 | 0.67 | — | — | |
| SCHEMBL24404178 | 0.67 | — | — | |
| SCHEMBL85991 | 0.67 | — | — | |
| SCHEMBL13283972 | 0.67 | — | — | |
| SCHEMBL965425 | 0.65 | — | — | |
| Potassium SCHEMBL30087616 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919495-A1 | INDOLO HEPTAMYL OXIME ANALOGUE AS PARP INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| US-10428044-B2 | 3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-01 | — | — | US | disclosed |
| EP-3066093-B9 | GSK-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-02-07 | — | — | EP | disclosed |
| EP-3066093-B1 | GSK-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-04 | — | — | EP | disclosed |
| US-20170101391-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| EP-2594568-A1 | Alpha-fluoroalkyl tetrabenazine and dihydrotetrabenazine imaging agents and probes | General Electric Company (US) | 2013-05-22 | — | — | EP | disclosed |
| US-20100234364-A1 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. | 2010-09-16 | — | — | US | disclosed |
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| EP-1622852-B1 | PROCESS OF REMOVING ORGANIC HALOGEN-CONTAINING COMPOUNDS | SHELL INT RESEARCH (NL) | 2007-04-04 | — | — | EP | disclosed |
| EP-1622852-A1 | PROCESS OF REMOVING ORGANIC HALOGEN-CONTAINING COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2006-02-08 | — | — | EP | disclosed |
| US-6909022-B2 | Process of removing organic halogen-containing compounds | SHELL OIL COMPANY (US) | 2005-06-21 | — | — | US | disclosed |
| US-20040267060-A1 | Process of removing organic halogen-containing compounds | SHELL USA, INC. | 2004-12-30 | — | — | US | disclosed |
| WO-2004101481-A1 | PROCESS OF REMOVING ORGANIC HALOGEN-CONTAINING COMPOUNDS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2004-11-25 | — | — | WO | disclosed |