Methacrylic Acid

Methacrylic Acid

SCHEMBL5188136

C=C(C)C(=O)O.C=C(CCCCCCCCCCCCCCCCCC)C(=O)O

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.57
FNTB P49356 2/20 0.57
THRB P10828 1/20 0.57
PGGT1B P53609 1/20 0.57
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL6445764 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL9816166 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL9004453 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL27470415 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL5722058 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL18255609 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL17530895 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL7627752 1.00 FNTA (0.57) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL4558399 0.98 FNTA (0.53) FNTAFNTBTHRBPGGT1BGPR84
Methacrylic Acid SCHEMBL6067698 0.96 FNTA (0.52) FNTAFNTBTHRBPGGT1BGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1789821-B1 SILICONE HYDROGEL CONTACT LENSES COOPERVISION INT HOLDING CO LP (BB) 2019-04-10 EP disclosed
US-9322958-B2 Silicone hydrogel contact lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2016-04-26 US disclosed
US-20150219795-A9 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL LIMITED (GB) 2015-08-06 US disclosed
US-20140200286-A1 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-07-17 US disclosed
US-8614261-B2 Silicone hydrogel contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY LP (BB) 2013-12-24 US disclosed
US-8367746-B2 Silicone hydrogel contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY (BB) 2013-02-05 US disclosed
US-20120252925-A1 Silicone Hydrogel Contact Lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-10-04 US disclosed
EP-1789821-A2 SILICONE HYDROGEL CONTACT LENSES ASAHIKASEI AIME CO., Ltd. (JP) 2007-05-30 EP disclosed
US-20070066706-A1 Silicone hydrogel contact lens COOPERVISION, INC. (US) 2007-03-22 US disclosed
US-20060063852-A1 Silicone hydrogel contact lens ASAHIKASEI AIME CO. LTD. (JP) 2006-03-23 US disclosed
WO-2006026474-A2 SILICONE HYDROGEL CONTACT LENSES ASAHIKASEI AIME CO. LTD. (JP) 2006-03-09 WO disclosed