Propylene Oxide

Propylene Oxide

SCHEMBL5188772

C=CC(=O)OCC(C)O.CC1CO1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
HPGD P15428 1/20 0.38
ALDH1A1 P00352 5/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27702309 0.85 TSHR (0.51) TSHRHPGDALDH1A1TP53HIF1A
Propylene Oxide SCHEMBL28096993 0.85 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27821519 0.85
SCHEMBL27800525 0.85
SCHEMBL33585 0.85
SCHEMBL2463533 0.84 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
Water SCHEMBL7201172 0.83 TSHR (0.72) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL29987278 0.83 TSHR (0.72) TSHRHPGDALDH1A1TP53HIF1A
Ammonia Solution, Strong SCHEMBL28656416 0.83 TSHR (0.72) TSHRHPGDALDH1A1TP53HIF1A
Hydrochloric Acid SCHEMBL11226745 0.83 TSHR (0.72) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177830-B1 Reaction method using heterogeneous catalyst and reaction apparatus therefor NIPPON CATALYTIC CHEM IND (JP) 2007-07-18 EP disclosed
EP-1177830-A2 Reaction method using heterogeneous catalyst and reaction apparatus therefor Nippon Shokubai Co., Ltd. (JP) 2002-02-06 EP disclosed