SCHEMBL5190429

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	2-Piperazin-1-Yl-Pyrimidine SCHEMBL1723933	0.84	KDM4E (0.60)	KDM4ECYP2C19RECQLRXFP1MAPT
	SCHEMBL20766983	0.84	CYP3A4 (0.54)	KDM4ECYP2C19RECQLCYP3A4ALDH1A1
	SCHEMBL195842	0.84	KDM4E (1.00)	KDM4ECYP2C19RXFP1MAPTTP53
	SCHEMBL20533493	0.83	CYP3A4 (0.53)	KDM4ECYP2C19RECQLCYP3A4ALDH1A1
	SCHEMBL12639917	0.82	KDM4E (0.72)	KDM4ECYP2C19RXFP1MAPTTP53
	SCHEMBL18255118	0.82	KDM4E (0.72)	KDM4ECYP2C19RXFP1MAPTTP53
	SCHEMBL12288871	0.81	HDAC6 (0.52)	KDM4ECYP2C19RECQLCYP3A4ALDH1A1
	SCHEMBL5101545	0.81	KDM4E (0.66)	KDM4ECYP2C19RXFP1MAPTTP53
	SCHEMBL15740759	0.81	KDM4E (0.49)	KDM4ECYP2C19RECQLCYP3A4ALDH1A1
	Hydrochloric Acid SCHEMBL5211735	0.80	KDM4E (0.64)	KDM4ECYP2C19RXFP1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.