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SCHEMBL5190845

SCHEMBL5190845

CCc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1.Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccccn1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 20/20 0.72
▸ CNR2 P34972 13/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL675155 0.89 CNR1 (0.90) CNR1CNR2
SCHEMBL674905 0.88 CNR1 (0.80) CNR1CNR2
SCHEMBL3683934 0.85 CNR1 (0.89) CNR1CNR2
SCHEMBL676438 0.84 CNR1 (1.00) CNR1CNR2
SCHEMBL2627869 0.84 CNR1 (1.00) CNR1CNR2
SCHEMBL5811129 0.83 CNR1 (0.86) CNR1CNR2
SCHEMBL2627871 0.82 CNR1 (0.89) CNR1CNR2
SCHEMBL4510012 0.81 CNR1 (0.77) CNR1CNR2
SCHEMBL4497043 0.81 CNR1 (0.77) CNR1CNR2
SCHEMBL6698425 0.81 CNR1 (0.88) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1807063-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS Solvay Pharmaceuticals GmbH (DE) 2007-07-18 — — EP disclosed
WO-2006045799-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS SOLVAY PHARMACEUTICALS GMBH (DE) 2006-05-04 — — WO disclosed