⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779845 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL5183542 | 0.71 | — | — | |
| SCHEMBL7070050 | 0.66 | — | — | |
| SCHEMBL18793253 | 0.65 | — | — | |
| SCHEMBL17084640 | 0.63 | — | — | |
| SCHEMBL22567268 | 0.63 | — | — | |
| SCHEMBL19928069 | 0.63 | — | — | |
| SCHEMBL10622154 | 0.63 | — | — | |
| SCHEMBL14627459 | 0.63 | — | — | |
| SCHEMBL22239847 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8128933-B2 | Method of promoting bone growth by an anti-activin B antibody | ACCELERON PHARMA, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090311252-A1 | Anti-activin antibodies and uses for promoting bone growth | ACCELERON PHARMA INC. (US) | 2009-12-17 | — | — | US | disclosed |