Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.72 |
| ▸ | CCR3 | P51677 | 20/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192663 | 0.92 | HRH1 (0.61) | HRH1CCR3KCNH2 | |
| SCHEMBL5194895 | 0.88 | CCR3 (0.57) | HRH1CCR3KCNH2 | |
| SCHEMBL5189859 | 0.84 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL5190328 | 0.84 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL5191532 | 0.84 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| Hydrochloric Acid SCHEMBL5196571 | 0.83 | HRH1 (0.98) | HRH1CCR3KCNH2 | |
| Hydrochloric Acid SCHEMBL5194871 | 0.83 | HRH1 (0.98) | HRH1CCR3KCNH2 | |
| SCHEMBL5190405 | 0.81 | HRH1 (0.51) | HRH1CCR3KCNH2 | |
| SCHEMBL4040955 | 0.81 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL4967102 | 0.80 | HRH1 (0.72) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816123-A1 | Intermediates for the production of pharmaceutically active compounds | AstraZeneca AB (SE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1546130-B1 | PIPERIDINE DERIVATIVES FOR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASE STATES | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | EP | disclosed |