Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.71 |
| ▸ | CCR3 | P51677 | 20/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192421 | 1.00 | HRH1 (0.71) | HRH1CCR3KCNH2 | |
| SCHEMBL5189755 | 1.00 | HRH1 (0.71) | HRH1CCR3KCNH2 | |
| SCHEMBL5193338 | 0.91 | HRH1 (0.69) | HRH1CCR3KCNH2 | |
| SCHEMBL4884868 | 0.90 | HRH1 (0.69) | HRH1CCR3KCNH2 | |
| SCHEMBL27632208 | 0.90 | HRH1 (0.64) | HRH1CCR3KCNH2 | |
| SCHEMBL4148060 | 0.86 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL5189941 | 0.86 | HRH1 (0.66) | HRH1CCR3KCNH2 | |
| SCHEMBL14110603 | 0.86 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL5191259 | 0.85 | HRH1 (0.65) | HRH1CCR3KCNH2 | |
| SCHEMBL5194606 | 0.85 | HRH1 (0.65) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816123-A1 | Intermediates for the production of pharmaceutically active compounds | AstraZeneca AB (SE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1546130-B1 | PIPERIDINE DERIVATIVES FOR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASE STATES | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | EP | disclosed |