SCHEMBL5193573

SCHEMBL5193573

C=CC(=O)OCCCC=C(O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
ALDH1A1 P00352 5/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 1/20 0.53
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.41
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28544460 0.82 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30679055 0.79 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30679047 0.79 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL865155 0.78 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20553764 0.77 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321925 0.77 TSHR (0.85) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL244114 0.77 TSHR (0.95) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29089161 0.76 TSHR (0.45) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2285652 0.76 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8493780 0.75 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209492-B1 Formation of materials such as waveguides with a refractive index step NAT UNIV IRELAND CORK (IE) 2004-02-04 EP claimed
CN-106457802-B Laminate, conductive roller, and method for producing laminate 株式会社普利司通 2018-04-13 CN disclosed
US-8916476-B2 Microfine structure formation method and microfine structure formed body HITACHI-LG DATA STORAGE, INC. (JP) 2014-12-23 US disclosed
US-20140231965-A1 MICROFINE STRUCTURE FORMATION METHOD AND MICROFINE STRUCTURE FORMED BODY HITACHI MEDIA ELECTRONICS CO., LTD. (JP) 2014-08-21 US disclosed
EP-1549700-B1 LAYER SYSTEM AND METHOD FOR PRODUCING THE SAME BAYER MATERIALSCIENCE AG (DE) 2007-08-01 EP disclosed
US-20070072124-A1 Optical recording composition, production method thereof and optical recording medium FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
EP-1633805-A1 METHOD FOR PRODUCING SCRATCH-RESISTANT COATING SYSTEMS DEVOID OF CONDENSATION Bayer MaterialScience AG (DE) 2006-03-15 EP disclosed
EP-1549701-A1 METHOD FOR PRODUCING A SCRATCH-RESISTANT LAYER SYSTEM Bayer MaterialScience AG (DE) 2005-07-06 EP disclosed
WO-2004108801-A1 METHOD FOR PRODUCING SCRATCH-RESISTANT COATING SYSTEMS DEVOID OF CONDENSATION BAYER MATERIALSCIENCE AG (DE) 2004-12-16 WO disclosed
WO-2004031272-A1 METHOD FOR PRODUCING A SCRATCH-RESISTANT LAYER SYSTEM BAYER MATERIALSCIENCE AG (DE) 2004-04-15 WO disclosed
EP-0424006-B1 Silane free radiation curable abrasion resistant coatings DOW CORNING (US) 1995-12-20 EP disclosed
US-5188900-A Substrates having an abrasion-resistant coating formed thereon DOW CORNING CORPORATION (US) 1993-02-23 US disclosed
US-5126394-A Silane-free DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
EP-0439294-A1 Alkoxy-functional silane compositions for unprimed adhesion to polycarbonate DOW CORNING CORPORATION (US) 1991-07-31 EP disclosed
EP-0439293-A1 Alkoxy-functional silane compositions for unprimed adhesion to polycarbonate DOW CORNING CORPORATION (US) 1991-07-31 EP disclosed
EP-0424006-A2 Silane free radiation curable abrasion resistant coatings DOW CORNING CORPORATION (US) 1991-04-24 EP disclosed
US-4358477-A Process of curing unsaturated epoxy coating composition with radiation and epoxy curing agent, and coated substrate AKZO N.V. (NL) 1982-11-09 US disclosed
EP-0008837-B1 RADIATION CURABLE LIQUID COATING COMPOSITION BASED ON AN EPOXY TERMINATED COMPOUND AND A PROCESS FOR COATING A SUBSTRATE WITH SUCH A COMPOSITION AKZO N.V. (NL) 1982-05-05 EP disclosed
EP-0008837-A1 Radiation curable liquid coating composition based on an epoxy terminated compound and a process for coating a substrate with such a composition AKZO N.V. (NL) 1980-03-19 EP disclosed
US-4173682-A ADDUCT OF HYDROXYALKYL ACRYLATE AND POLYISOCYANATE AKZO N.V. (NL) 1979-11-06 US disclosed