Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194744 | 0.81 | GRM2 (0.38) | GRM2RIPK1KCNQ4KCNQ5HTR2C | |
| SCHEMBL4765343 | 0.77 | GRM2 (0.42) | GRM2RIPK1KCNQ4KCNQ5HTR2C | |
| SCHEMBL4767547 | 0.77 | GRM2 (0.40) | GRM2RIPK1HTR2CSLC6A4MAPT | |
| SCHEMBL29555338 | 0.77 | KCNQ4 (0.50) | GRM2RIPK1KCNQ4KCNQ5HTR2C | |
| SCHEMBL12715855 | 0.76 | GRM2 (0.43) | GRM2RIPK1HTR2CSLC6A4HTR2A | |
| SCHEMBL5191856 | 0.76 | GRM2 (0.45) | GRM2RIPK1HTR2CSLC6A4HTR2A | |
| SCHEMBL4772593 | 0.76 | GRM2 (0.39) | GRM2RIPK1KCNQ4KCNQ5HTR2C | |
| SCHEMBL5773500 | 0.72 | GRM2 (0.38) | GRM2RIPK1KCNQ4KCNQ5HTR2C | |
| SCHEMBL5191594 | 0.72 | SNCA (0.49) | GRM2MAPT | |
| SCHEMBL25366767 | 0.71 | KCNQ4 (0.50) | GRM2RIPK1KCNQ4KCNQ5HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |