Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.74 |
| ▸ | FLT3 | P36888 | 10/20 | 0.74 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.62 |
| ▸ | CDK1 | P06493 | 8/20 | 0.62 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.62 |
| ▸ | CDK4 | P11802 | 3/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.62 |
| ▸ | CCND1 | P24385 | 3/20 | 0.62 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.57 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195168 | 1.00 | CDK2 (0.74) | CDK2FLT3PDGFRACCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL5626378 | 0.99 | CDK2 (0.73) | CDK2FLT3PDGFRACCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL5626380 | 0.99 | CDK2 (0.73) | CDK2FLT3PDGFRACCNE1CDK1 | |
| SCHEMBL5194044 | 0.92 | CDK2 (0.72) | CDK2FLT3PDGFRACCNE1CDK1 | |
| SCHEMBL5194040 | 0.92 | CDK2 (0.72) | CDK2FLT3PDGFRACCNE1CDK1 | |
| SCHEMBL5193994 | 0.92 | CDK2 (0.74) | CDK2FLT3PDGFRACCNE1CDK1 | |
| SCHEMBL5193991 | 0.92 | CDK2 (0.74) | CDK2FLT3PDGFRACCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL5628105 | 0.91 | CDK2 (0.71) | CDK2FLT3PDGFRACCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL5628107 | 0.91 | CDK2 (0.71) | CDK2FLT3PDGFRACCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL5627184 | 0.91 | CDK2 (0.73) | CDK2FLT3PDGFRACCNE1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183256-B1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2007-08-22 | — | — | EP | disclosed |
| EP-1183256-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071543-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-11-30 | — | — | WO | disclosed |