Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.59 |
| ▸ | CDK1 | P06493 | 8/20 | 0.59 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.59 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.59 |
| ▸ | CDK4 | P11802 | 3/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.59 |
| ▸ | CCND1 | P24385 | 3/20 | 0.59 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.59 |
| ▸ | FLT3 | P36888 | 11/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195515 | 1.00 | CDK2 (0.59) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL5626259 | 0.99 | CDK2 (0.58) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL5197207 | 0.91 | CDK2 (0.63) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL5197196 | 0.91 | CDK2 (0.63) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL5626846 | 0.90 | CDK2 (0.62) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL5193416 | 0.90 | CDK2 (0.62) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL5196569 | 0.90 | FLT3 (0.66) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL5626851 | 0.90 | CDK2 (0.62) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL5196559 | 0.90 | FLT3 (0.66) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL5193425 | 0.90 | CDK2 (0.62) | CDK2CCNE1CDK1CCNE2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183256-B1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2007-08-22 | — | — | EP | disclosed |
| EP-1183256-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071543-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-11-30 | — | — | WO | disclosed |