Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5182227 | 0.99 | CETP (0.40) | CETP | |
| SCHEMBL1897996 | 0.95 | CETP (0.39) | CETP | |
| SCHEMBL1899214 | 0.94 | CETP (0.39) | CETP | |
| Hydrochloric Acid SCHEMBL1904689 | 0.93 | CETP (0.42) | CETP | |
| Bicarbonate SCHEMBL5211571 | 0.93 | CETP (0.39) | CETP | |
| SCHEMBL4831047 | 0.93 | CETP (0.43) | CETP | |
| Hydrochloric Acid SCHEMBL1899526 | 0.92 | CETP (0.42) | CETP | |
| Bicarbonate SCHEMBL5180403 | 0.92 | CETP (0.39) | CETP | |
| SCHEMBL4830846 | 0.91 | CETP (0.43) | CETP | |
| Bicarbonate SCHEMBL5192359 | 0.89 | CETP (0.32) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1533292-B1 | DIBENZYLAMINE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2007-02-14 | — | — | EP | claimed |