Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761350 | 0.81 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL2300769 | 0.81 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL5221981 | 0.80 | PTGER4 (0.69) | PTGER4 | |
| SCHEMBL3564831 | 0.78 | PTGER4 (0.80) | PTGER4 | |
| SCHEMBL3557625 | 0.77 | PTGER4 (0.78) | PTGER4 | |
| SCHEMBL3567548 | 0.77 | PTGER4 (0.94) | PTGER4 | |
| SCHEMBL4620079 | 0.77 | PTGER4 (0.68) | PTGER4 | |
| SCHEMBL3561049 | 0.77 | PTGER4 (0.94) | PTGER4 | |
| SCHEMBL5427620 | 0.77 | PTGER4 (0.68) | PTGER4 | |
| SCHEMBL3567596 | 0.76 | PTGER4 (0.90) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368312-B1 | BENZO[F]ISOINDOLE DERIVATIVES WITH AFFINITY TO THE EP4 RECEPTOR | GLAXO GROUP LTD (GB) | 2007-06-27 | — | — | EP | disclosed |
| EP-1368312-A1 | BENZO'F!ISOINDOLE DERIVATIVES WITH AFFINITY TO THE EP4 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002064564-A1 | BENZO'F!ISOINDOLE DERIVATIVES WITH AFFINITY TO THE EP4 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2002-08-22 | — | — | WO | disclosed |
| WO-2002047669-A1 | USE OF EP4 RECEPTOR AGONISTS FOR TREATING NEUROPATHIC PAIN | GLAXO GROUP LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |