Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 20/20 | 0.77 |
| ▸ | CCNE1 | P24864 | 20/20 | 0.77 |
| ▸ | CDK2 | P24941 | 20/20 | 0.77 |
| ▸ | CCNA2 | P20248 | 19/20 | 0.77 |
| ▸ | CCNA1 | P78396 | 19/20 | 0.77 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.68 |
| ▸ | CDK1 | P06493 | 1/20 | 0.68 |
| ▸ | CDK4 | P11802 | 1/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.68 |
| ▸ | CCND1 | P24385 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 1/20 | 0.68 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195310 | 1.00 | CCNE2 (0.77) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Cadaverine Tartrate SCHEMBL5628833 | 0.93 | CCNE2 (0.69) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL5195563 | 0.93 | CCNE2 (0.75) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL5195558 | 0.93 | CCNE2 (0.75) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL6821200 | 0.93 | CCNE2 (0.90) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL6821203 | 0.93 | CCNE2 (0.90) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6824017 | 0.92 | CCNE2 (0.88) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6820812 | 0.92 | CCNE2 (0.88) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6820813 | 0.92 | CCNE2 (0.88) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6821251 | 0.92 | CCNE2 (0.88) | CCNE2CCNE1CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183256-B1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2007-08-22 | — | — | EP | disclosed |
| US-7122669-B1 | Purine derivatives, preparation method and pharmaceutical compositions containing same | HOECHST MARION ROUSSEL (FR) | 2006-10-17 | — | — | US | disclosed |