SCHEMBL5196282

SCHEMBL5196282

CC(C)(C)OC(=O)CC[C@@H](CBr)NC(=O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.58
CTRB1 P17538 2/20 0.49
MAPT P10636 1/20 0.47
CTSK P43235 5/20 0.45
ATM Q13315 2/20 0.45
CTSL P07711 2/20 0.44
CTSS P25774 2/20 0.44
CTSB P07858 1/20 0.44
PPARA Q07869 1/20 0.42
CASP1 P29466 1/20 0.42
ELANE P08246 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143120 0.89 SYK (0.60) SYKCTRB1MAPTCTSKATM
SCHEMBL1556449 0.89 SYK (0.60) SYKCTRB1MAPTCTSKATM
SCHEMBL12849605 0.89 SYK (0.69) SYKCTRB1MAPTCTSKATM
SCHEMBL19401966 0.88 SYK (0.58) SYKCTRB1MAPTCTSKATM
SCHEMBL19401968 0.88 SYK (0.58) SYKCTRB1MAPTCTSKATM
SCHEMBL31532282 0.88 SYK (0.58) SYKCTRB1MAPTCTSKATM
SCHEMBL1555741 0.87 SYK (0.57) SYKCTRB1MAPTCTSKATM
SCHEMBL1555742 0.87 SYK (0.57) SYKCTRB1MAPTCTSKATM
SCHEMBL143176 0.86 SYK (0.56) SYKCTRB1MAPTCTSKATM
SCHEMBL21834805 0.85 SYK (0.55) SYKCTRB1MAPTCTSKATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340756-B1 NOVEL BETA-LACTAM COMPOUNDS AND PROCESS FOR PRODUCING THE SAME DAINIPPON SUMITOMO PHARMA CO (JP) 2007-10-10 EP disclosed
US-7163936-B2 β-lactam compounds and process for producing the same DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-01-16 US disclosed
US-20040102433-A1 Novel beta-lactam compounds and process for producing the same DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2004-05-27 US disclosed
EP-1340756-A1 NOVEL BETA-LACTAM COMPOUNDS AND PROECSS FOR PRODUCING THE SAME SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102433-A1 Novel beta-lactam compounds and process for producing the same MRPL21, MCRS1, RPS4X SYK 2797/4885CTRB1 941/4885MAPT 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.