Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819039 | 0.84 | PPARA (0.46) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20837204 | 0.83 | KCNN4 (0.48) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10837067 | 0.82 | KCNN4 (0.62) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2517938 | 0.82 | KCNN4 (0.50) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22722985 | 0.82 | KCNN4 (0.50) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5046100 | 0.82 | KCNN4 (0.50) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10710486 | 0.80 | CES1 (0.48) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19275896 | 0.78 | CES1 (0.47) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15120026 | 0.78 | CES1 (0.47) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4554194 | 0.78 | MAPT (0.59) | KCNN4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110087466-B | Active compound combinations | 拜耳作物科学股份公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-1737840-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005103033-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2005-11-03 | — | — | WO | disclosed |