Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | F7 | P08709 | 5/20 | 0.72 |
| ▸ | F3 | P13726 | 5/20 | 0.72 |
| ▸ | PPARD | Q03181 | 5/20 | 0.72 |
| ▸ | PPARA | Q07869 | 5/20 | 0.72 |
| ▸ | FABP4 | P15090 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.72 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linoleic Acid SCHEMBL29185362 | 0.96 | PPARG (0.79) | PPARGALDH1A1F7F3PPARD | |
| Stearic Acid SCHEMBL6898448 | 0.96 | PPARG (0.79) | PPARGALDH1A1F7F3PPARD | |
| Stearic Acid SCHEMBL6897182 | 0.96 | PPARG (0.79) | PPARGALDH1A1F7F3PPARD | |
| Oleic Acid SCHEMBL10942132 | 0.91 | EPHX2 (0.77) | PPARGALDH1A1F7F3PPARD | |
| Oleic Acid SCHEMBL10388080 | 0.91 | EPHX2 (0.77) | PPARGALDH1A1F7F3PPARD | |
| Oleic Acid SCHEMBL10388079 | 0.91 | EPHX2 (0.77) | PPARGALDH1A1F7F3PPARD | |
| Oleic Acid SCHEMBL6156883 | 0.91 | EPHX2 (0.77) | PPARGALDH1A1F7F3PPARD | |
| Dymanthine SCHEMBL5881102 | 0.91 | EPHX2 (0.77) | PPARGALDH1A1F7F3PPARD | |
| Dymanthine SCHEMBL5881103 | 0.91 | EPHX2 (0.77) | PPARGALDH1A1F7F3PPARD | |
| Stearic Acid SCHEMBL6898222 | 0.91 | EPHX2 (0.77) | PPARGALDH1A1F7F3PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470492-A | Dryer-activated fabric conditioning articles with soft polyester substrate | THE PROCTER & GAMBLE COMPANY (US) | 1995-11-28 | — | — | US | claimed |
| EP-1282682-B1 | ANTIMICROBIAL TRANSFER SUBSTRATES AND METHODS OF USE THEREWITH | MILLIKEN & CO (US) | 2007-05-16 | — | — | EP | disclosed |
| EP-1282683-B1 | ANTIMICROBIAL TRANSFER SUBSTRATES AND METHODS OF USE THEREWITH | MILLIKEN & CO (US) | 2006-10-11 | — | — | EP | disclosed |
| EP-1282683-A1 | ANTIMICROBIAL TRANSFER SUBSTRATES AND METHODS OF USE THEREWITH | Milliken & Company (US) | 2003-02-12 | — | — | EP | disclosed |
| EP-1282682-A1 | ANTIMICROBIAL TRANSFER SUBSTRATES AND METHODS OF USE THEREWITH | Milliken & Company (US) | 2003-02-12 | — | — | EP | disclosed |
| US-6461386-B1 | FABRIC SOFTENERS | MILLIKEN & COMPANY | 2002-10-08 | — | — | US | disclosed |
| US-6454813-B1 | POLYOLEFIN DONOR FABRICS (IN SHEET FORM, FOR EXAMPLE), ARE AN EFFECTIVE TRANSFER MECHANISM FOR ANTIMICROBIAL DEPOSITION SUCH AS OF ZINC OXIDE OR SILVER-BASED ION EXCHANGE MATERIAL ON THE RECIPIENT FABRICS SUCH AS IN A TUMBLE DRYER | MILLIKEN & COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-20020023304-A1 | Antimicrobial transfer substrates and methods of use therewith | CHAN MARIE S (US) | 2002-02-28 | — | — | US | disclosed |
| WO-2001088081-A1 | ANTIMICROBIAL TRANSFER SUBSTRATES AND METHODS OF USE THEREWITH | MILLIKEN & COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001088080-A1 | ANTIMICROBIAL TRANSFER SUBSTRATES AND METHODS OF USE THEREWITH | MILLIKEN & COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |