Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197894 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL5197907 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL5195953 | 0.96 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL5195975 | 0.96 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL5195969 | 0.96 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10155800 | 0.96 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10156319 | 0.96 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10156090 | 0.92 | ADORA2A (0.64) | ADORA2AADORA3ADORA1ADORA2B | |
| Trifluoroacetic Acid SCHEMBL3907185 | 0.89 | ADORA2A (0.60) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4231219 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861412-A1 | ADENOSINE DERIVATIVES HAVING A2A RECEPTOR ACTIVITY | Novartis AG (CH) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006097260-A1 | ADENOSINE DERIVATIVES HAVING A2A RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2006-09-21 | — | — | WO | disclosed |