Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231078 | 0.88 | ADORA2A (0.56) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4231106 | 0.88 | ADORA2A (0.56) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4147066 | 0.88 | ADORA2A (0.51) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4159761 | 0.88 | ADORA2A (0.52) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| Water SCHEMBL4239095 | 0.88 | ADORA2A (0.55) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| Water SCHEMBL4239105 | 0.88 | ADORA2A (0.55) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4164803 | 0.85 | ADORA2A (0.54) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4152301 | 0.84 | ADORA2A (0.55) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4148702 | 0.83 | ADORA2A (0.57) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4149730 | 0.82 | ADORA2A (0.57) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805196-A1 | SUBSTITUTED ADENINES AND THE USE THEREOF | AstraZeneca AB (SE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006040558-A1 | SUBSTITUTED ADENINES AND THE USE THEREOF | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |