Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 17/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214527 | 0.91 | MC4R (0.43) | MC4R | |
| SCHEMBL5458234 | 0.91 | MC4R (0.43) | MC4R | |
| SCHEMBL5214537 | 0.91 | MC4R (0.43) | MC4R | |
| SCHEMBL5454784 | 0.91 | MC4R (0.46) | MC4RCYP51A1MC5RMC3RMC1R | |
| SCHEMBL5449594 | 0.91 | CYP51A1 (0.44) | MC4RCCR1CYP51A1MC5RMC3R | |
| SCHEMBL5454406 | 0.91 | MC4R (0.45) | MC4RCCR1 | |
| SCHEMBL5451683 | 0.90 | MC4R (0.45) | MC4RCYP51A1MC5RMC3RMC1R | |
| SCHEMBL5453848 | 0.90 | MC4R (0.45) | MC4RCYP51A1MC5RMC3RMC1R | |
| SCHEMBL5465381 | 0.90 | MC4R (0.45) | MC4RCYP51A1MC5RMC3RMC1R | |
| SCHEMBL5456724 | 0.90 | MC4R (0.43) | MC4RCYP51A1MC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786809-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | Sanofi-Aventis (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021656-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |