Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 16/20 | 0.67 |
| ▸ | FLT3 | P36888 | 14/20 | 0.67 |
| ▸ | FLT4 | P35916 | 13/20 | 0.67 |
| ▸ | CSF1R | P07333 | 12/20 | 0.67 |
| ▸ | KDR | P35968 | 6/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526346 | 0.84 | PDGFRB (0.69) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4525364 | 0.82 | PDGFRB (0.76) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4524898 | 0.81 | PDGFRB (0.75) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4532891 | 0.81 | PDGFRB (0.75) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4515269 | 0.79 | PDGFRB (0.73) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4521765 | 0.79 | PDGFRB (0.81) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4518073 | 0.79 | PDGFRB (0.69) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4529649 | 0.79 | PDGFRB (0.73) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4531905 | 0.79 | PDGFRB (0.72) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4533976 | 0.79 | PDGFRB (0.72) | PDGFRBFLT3FLT4CSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802608-A1 | QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER | AstraZeneca AB (SE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040526-A1 | QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |