⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049831 | 0.74 | — | — | |
| SCHEMBL29615421 | 0.67 | — | — | |
| SCHEMBL511838 | 0.60 | — | — | |
| SCHEMBL9616056 | 0.60 | — | — | |
| SCHEMBL5071024 | 0.58 | — | — | |
| SCHEMBL2422256 | 0.58 | — | — | |
| SCHEMBL9042449 | 0.58 | — | — | |
| SCHEMBL692413 | 0.57 | — | — | |
| SCHEMBL3149572 | 0.55 | — | — | |
| SCHEMBL3851657 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070098807-A1 | Matrices for drug delivery and methods for making and using the same | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2007-05-03 | — | — | US | disclosed |
| US-7052913-B2 | Matrices for drug delivery and methods for making and using the same | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040241205-A1 | Matrices for drug delivery and methods for making and using the same | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2004-12-02 | — | — | US | disclosed |
| US-20030082238-A1 | Matrices for drug delivery and methods for making and using the same | BABICH JOHN W (US) | 2003-05-01 | — | — | US | disclosed |
| US-6423519-B1 | CONTACTING FUNGAL CELL WITH COMPOUND WHICH INHIBITS PRENYLTRANSFERASE ACTIVITY OF CELL, INCLUDING PERMEASE TAG WHICH FACILITATES PERMEASE-MEDIATED TRANSPORT OF COMPOUND INTO CELL, INHIBITING GROWTH THEREOF | GPC BIOTECH INC. | 2002-07-23 | — | — | US | disclosed |
| US-6395299-B1 | PARKINSON'S DISEASE | BIOSTREAM, INC. | 2002-05-28 | — | — | US | disclosed |
| EP-1096925-A2 | USE OF INHIBITORS OF PRENYLTRANSFERASES FOR FOR INHIBITING FUNGAL GROWTH | MITOTIX, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000047236-A1 | MATRICES FOR DRUG DELIVERY AND METHODS FOR MAKING AND USING THE SAME | BIOSTREAM, INC. (US) | 2000-08-17 | — | — | WO | disclosed |
| WO-2000003743-A9 | USE OF INHIBITORS OF PRENYLTRANSFERASES FOR INHIBITING FUNGAL GROWTH | MITOTIX INC (US) | 2000-07-27 | — | — | WO | disclosed |
| WO-2000003743-A2 | USE OF INHIBITORS OF PRENYLTRANSFERASES FOR INHIBITING FUNGAL GROWTH | MITOTIX, INC. (US) | 2000-01-27 | — | — | WO | disclosed |
| US-5776902-A | Boronophenyl analogs of phospholyrosines | TRUSTEES OF TUFTS UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0731803-A4 | NOVEL FURANODIAZEPINES | MERCK & CO INC (US) | 1997-06-18 | — | — | EP | disclosed |
| US-5580979-A | Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions | TRUSTEES OF TUFTS UNIVERSITY (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0731803-A1 | NOVEL FURANODIAZEPINES | MERCK & CO. INC. (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5453424-A | Furanodiazepines | MERCK & CO., INC. (US) | 1995-09-26 | — | — | US | disclosed |
| US-5453424-A | Furanodiazepines | MERCK & CO., INC. (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1995025118-A2 | INHIBITORS OF SH2 DOMAIN INTERACTIONS | TRUSTEES OF TUFTS UNIVERSITY (US) | 1995-09-21 | — | — | WO | disclosed |
| WO-1995014695-A1 | NOVEL FURANODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |