Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231328 | 0.86 | ADORA2A (0.64) | ADORA2AADORA2BADORA3 | |
| SCHEMBL5197885 | 0.85 | ADORA2A (0.60) | ADORA2AADORA2BADORA3 | |
| SCHEMBL3882647 | 0.84 | ADORA2A (0.54) | ADORA2AADORA2BADORA3 | |
| SCHEMBL5198406 | 0.81 | ADORA2A (0.54) | ADORA2AADORA2BADORA3 | |
| SCHEMBL3878110 | 0.79 | ADORA2A (0.47) | ADORA2AADORA2BADORA3 | |
| SCHEMBL3879857 | 0.79 | ADORA2A (0.75) | ADORA2AADORA2BADORA3 | |
| SCHEMBL14396879 | 0.78 | ADORA2A (0.63) | ADORA2AADORA2BADORA3 | |
| SCHEMBL4152279 | 0.78 | ADORA2A (0.71) | ADORA2AADORA2BADORA3 | |
| SCHEMBL13855940 | 0.77 | ADORA2A (0.62) | ADORA2AADORA2BADORA3 | |
| SCHEMBL4147086 | 0.77 | ADORA2A (0.61) | ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805196-A1 | SUBSTITUTED ADENINES AND THE USE THEREOF | AstraZeneca AB (SE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006040558-A1 | SUBSTITUTED ADENINES AND THE USE THEREOF | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |