Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL460343 | 1.00 | TDP1 (0.71) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Acrylamide SCHEMBL28724334 | 1.00 | TDP1 (0.71) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Acrylamide SCHEMBL11695128 | 0.97 | TDP1 (0.67) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Acrylamide SCHEMBL6154282 | 0.97 | TDP1 (0.67) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Acrylamide SCHEMBL9179971 | 0.97 | TDP1 (0.67) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Acrylamide SCHEMBL28189131 | 0.95 | TDP1 (0.63) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Cyclohexane SCHEMBL11172203 | 0.92 | TDP1 (0.60) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Methacrylic Acid SCHEMBL28878259 | 0.92 | TDP1 (0.60) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| SCHEMBL28208235 | 0.88 | TDP1 (0.71) | TDP1ALDH1A1TSHRFGFR4TP53 | |
| Acrylamide SCHEMBL23493546 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439220-B1 | Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions | ADORKEM TECHNOLOGY SPA (IT) | 2007-08-22 | — | — | EP | claimed |
| US-20040142438-A1 | Novel immobilized biocatalysts usable for the production of natural nucleosides and modified analogues by enzymatic transglycosylation reactions | KERYOS SPA (IT) | 2004-07-22 | — | — | US | claimed |
| EP-1439220-A1 | Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions | Keryos Spa (IT) | 2004-07-21 | — | — | EP | claimed |
| EP-1439220-B1 | Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions | ADORKEM TECHNOLOGY SPA (IT) | 2007-08-22 | — | — | EP | disclosed |
| US-20040142438-A1 | Novel immobilized biocatalysts usable for the production of natural nucleosides and modified analogues by enzymatic transglycosylation reactions | KERYOS SPA (IT) | 2004-07-22 | — | — | US | disclosed |
| EP-1439220-A1 | Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions | Keryos Spa (IT) | 2004-07-21 | — | — | EP | disclosed |