SCHEMBL5199702

SCHEMBL5199702

O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 3/20 0.76
IL2 P60568 3/20 0.76
TDP1 Q9NUW8 2/20 0.76
L3MBTL1 Q9Y468 2/20 0.76
HSD17B10 Q99714 1/20 0.76
KDM4E B2RXH2 1/20 0.76
MEN1 O00255 1/20 0.76
ALDH1A1 P00352 1/20 0.76
MAPT P10636 1/20 0.76
RECQL P46063 1/20 0.76
KMT2A Q03164 1/20 0.76
SMN1; SMN2 Q16637 2/20 0.64
SLCO2B1 O94956 1/20 0.64
KDM1A O60341 1/20 0.62
XDH P47989 1/20 0.61
CA12 O43570 3/20 0.60
CA9 Q16790 3/20 0.60
CA1 P00915 2/20 0.60
CA2 P00918 1/20 0.60
NPC1 O15118 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14430867 1.00 TNF (0.76) TNFIL2TDP1L3MBTL1HSD17B10
SCHEMBL15387396 0.91 TNF (0.67) TNFIL2TDP1L3MBTL1HSD17B10
SCHEMBL22568831 0.90 SMN1; SMN2 (0.75) TNFIL2TDP1L3MBTL1HSD17B10
SCHEMBL30266664 0.87 TNF (0.71) TNFIL2TDP1L3MBTL1HSD17B10
SCHEMBL4649434 0.87 HSD17B10 (0.66) TNFIL2TDP1L3MBTL1HSD17B10
SCHEMBL11304299 0.87 HSD17B10 (0.66) TNFIL2TDP1L3MBTL1HSD17B10
Galuteolin SCHEMBL149118 0.86 MEN1 (1.00) TNFIL2TDP1L3MBTL1HSD17B10
Galuteolin SCHEMBL22510086 0.86 MEN1 (1.00) TNFIL2TDP1L3MBTL1HSD17B10
Galuteolin SCHEMBL16755609 0.86 MEN1 (1.00) TNFIL2TDP1L3MBTL1HSD17B10
Galuteolin SCHEMBL2126750 0.86 MEN1 (1.00) TNFIL2TDP1L3MBTL1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1818060-A1 Cosmetic composition comprising Fadogia ancylantha extracts ARTSANA S.p.A. (IT) 2007-08-15 EP claimed
EP-1818060-A1 Cosmetic composition comprising Fadogia ancylantha extracts ARTSANA S.p.A. (IT) 2007-08-15 EP disclosed