SCHEMBL5199825

SCHEMBL5199825

CC(=O)Oc1ccc(Cl)cc1CN1CCN(S(=O)(=O)c2ccccc2)[C@@H](C)C1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1714650 1.00 PTGDR2 (0.78) PTGDR2
SCHEMBL27748368 0.91 PTGDR2 (0.76) PTGDR2
SCHEMBL27852054 0.91 PTGDR2 (0.76) PTGDR2
SCHEMBL28773838 0.88 PTGDR2 (0.60) PTGDR2
SCHEMBL1713844 0.88 PTGDR2 (1.00) PTGDR2
SCHEMBL1714725 0.88 PTGDR2 (1.00) PTGDR2
SCHEMBL1714027 0.88 PTGDR2 (1.00) PTGDR2
SCHEMBL5201562 0.87 PTGDR2 (0.73) PTGDR2
SCHEMBL4608065 0.87 PTGDR2 (0.73) PTGDR2
SCHEMBL1714468 0.86 PTGDR2 (1.00) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101356164-A Novel compounds ASTRAZENECA AB (SE) 2009-01-28 CN claimed
CN-101356164-A Novel compounds ASTRAZENECA AB (SE) 2009-01-28 CN disclosed
EP-1817282-A1 PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES AstraZeneca AB (SE) 2007-08-15 EP disclosed
WO-2006056752-A1 PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES ASTRAZENECA AB (SE) 2006-06-01 WO disclosed