⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732414 | 0.80 | — | — | |
| SCHEMBL2286486 | 0.76 | — | — | |
| SCHEMBL700169 | 0.74 | CYP1A2 (0.36) | — | |
| SCHEMBL6678060 | 0.67 | ITGB2 (0.39) | — | |
| SCHEMBL8654222 | 0.67 | — | — | |
| SCHEMBL14275641 | 0.67 | — | — | |
| SCHEMBL5071187 | 0.67 | — | — | |
| SCHEMBL14303110 | 0.67 | CYP1A2 (0.42) | — | |
| SCHEMBL27575 | 0.67 | — | — | |
| SCHEMBL14890331 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598350-B1 | Pyrrolidines and thiazolidines derivatives, their preparation and their use in the treatment of hyperglycaemia and of type II Diabetis | SERVIER LAB (FR) | 2007-07-11 | — | — | EP | disclosed |
| EP-1598350-A1 | Pyrrolidines and thiazolidines derivatives, their preparation and their use in the treatment of hyperglycaemia and of type II Diabetis | LES LABORATOIRES SERVIER (FR) | 2005-11-23 | — | — | EP | disclosed |