Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | SQLE | Q14534 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834686 | 0.96 | NR1I2 (0.68) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL2836407 | 0.96 | NR1I2 (0.68) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL2833805 | 0.96 | NR1I2 (0.68) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL2836836 | 0.96 | NR1I2 (0.68) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL2832876 | 0.96 | NR1I2 (0.68) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL116153 | 0.93 | NR1I2 (0.71) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL116152 | 0.93 | NR1I2 (0.71) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL2833053 | 0.91 | NR1I2 (0.50) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL2838337 | 0.91 | NR1I2 (0.50) | NR1I2LMNAPGRALOX15FNTA | |
| SCHEMBL2840460 | 0.91 | NR1I2 (0.50) | NR1I2LMNAPGRALOX15FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070014734-A1 | Glucuronidated nebivolol metabolites | MYLAN INC. (F/K/A MYLAN LABORATORIES INC.) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070014734-A1 | Glucuronidated nebivolol metabolites | UGT1A4, UGT1A3, UGT1A1 | NR1I2 241/4885LMNA 1082/4885PGR 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.