Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
| ▸ | CASP5 | P51878 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397973 | 0.74 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DHRH1 | |
| SCHEMBL3319161 | 0.73 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DHRH4 | |
| SCHEMBL10709061 | 0.73 | PDE4A (0.97) | PDE4APDE4BPDE4CPDE4DHRH1 | |
| SCHEMBL1720095 | 0.73 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DHRH1 | |
| SCHEMBL3326385 | 0.71 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DHRH1 | |
| SCHEMBL1719680 | 0.70 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DHTR2A | |
| SCHEMBL3322406 | 0.70 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DHTR3A | |
| SCHEMBL3321848 | 0.69 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DHRH1 | |
| SCHEMBL3321333 | 0.68 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DHRH1 | |
| SCHEMBL1720035 | 0.67 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819708-A2 | SUBSTITUTED PTERIDINES FOR TREATING INFLAMMATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058868-A2 | SUBSTITUTED PTERIDINES FOR TREATING INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |