Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.53 |
| ▸ | CNR2 | P34972 | 10/20 | 0.53 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064687 | 1.00 | CNR1 (0.53) | CNR1CNR2FDFT1GAAHPGD | |
| SCHEMBL4823362 | 1.00 | CNR1 (0.53) | CNR1CNR2FDFT1GAAHPGD | |
| SCHEMBL4823367 | 1.00 | CNR1 (0.53) | CNR1CNR2FDFT1GAAHPGD | |
| SCHEMBL14064685 | 1.00 | CNR1 (0.53) | CNR1CNR2FDFT1GAAHPGD | |
| SCHEMBL4831250 | 1.00 | CNR1 (0.53) | CNR1CNR2FDFT1GAAHPGD | |
| SCHEMBL4829860 | 0.94 | CNR1 (0.52) | CNR1CNR2FDFT1 | |
| SCHEMBL4825560 | 0.90 | CNR1 (0.50) | CNR1CNR2FDFT1GAAHPGD | |
| SCHEMBL3594447 | 0.86 | CNR1 (0.50) | CNR1CNR2FDFT1GAAHPGD | |
| SCHEMBL4827963 | 0.85 | CNR1 (0.50) | CNR1CNR2FDFT1 | |
| SCHEMBL4822199 | 0.85 | CNR1 (0.50) | CNR1CNR2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490043-A4 | SPIROCYCLIC AMIDES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO INC (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1490043-A2 | SPIROCYCLIC AMIDES AS CANNABINOID RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082190-A2 | SPIROCYCLIC AMIDES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | disclosed |