Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 16/20 | 0.61 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 15/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 15/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206070 | 0.88 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5206081 | 0.88 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5206692 | 0.85 | ITGAL (0.58) | ITGALARITGB2ICAM1 | |
| SCHEMBL5203623 | 0.85 | ITGAL (0.58) | ITGALARITGB2ICAM1 | |
| SCHEMBL5204304 | 0.77 | ITGB2 (0.62) | ITGALARITGB2ICAM1 | |
| SCHEMBL7130481 | 0.77 | ITGB2 (0.62) | ITGALARITGB2ICAM1 | |
| SCHEMBL6314324 | 0.76 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL6314317 | 0.76 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL13879533 | 0.76 | ITGAL (0.76) | ITGALARITGB2ICAM1 | |
| SCHEMBL1772990 | 0.72 | AR (0.56) | ITGALAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284973-B1 | INHIBITORS OF ALPHA L BETA 2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1284973-B1 | INHIBITORS OF ALPHA L BETA 2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-6699888-B2 | ANTIINFLAMMATORY | TANABE SEIYAKU CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |