Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | APLNR | P35414 | 5/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14177407 | 0.95 | S1PR3 (0.58) | S1PR3S1PR1HRH4HRH3ALOX15 | |
| SCHEMBL14177391 | 0.93 | S1PR3 (0.44) | S1PR3S1PR1APLNRHRH4HRH3 | |
| SCHEMBL3002137 | 0.93 | S1PR3 (0.44) | S1PR3S1PR1APLNRHRH4HRH3 | |
| SCHEMBL5103713 | 0.88 | S1PR3 (0.49) | S1PR3S1PR1HRH4HRH3 | |
| SCHEMBL5110271 | 0.88 | S1PR1 (0.42) | S1PR3S1PR1HRH4HRH3MEN1 | |
| SCHEMBL3000064 | 0.85 | S1PR3 (0.44) | S1PR3S1PR1APLNRBRD4BRD2 | |
| SCHEMBL14277106 | 0.85 | HRH4 (0.45) | S1PR3S1PR1APLNRHRH4HRH3 | |
| SCHEMBL14177382 | 0.85 | HRH4 (0.45) | S1PR3S1PR1HRH4HRH3PIN1 | |
| SCHEMBL14177377 | 0.84 | MEN1 (0.45) | S1PR3S1PR1APLNRHRH4HRH3 | |
| SCHEMBL5109670 | 0.84 | MEN1 (0.40) | S1PR3S1PR1HRH4HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807086-A1 | USE OF DIPYRIDAMOLE IN COMBINATION WITH ANTITHROMBOTICS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISEASES | Boehringer Ingelheim International GmbH (DE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006045756-A1 | USE OF DIPYRIDAMOLE IN COMBINATION WITH ANTITHROMBOTICS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-04 | — | — | WO | disclosed |