SCHEMBL5202218

SCHEMBL5202218

COC=C(C)C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17755551 0.77
SCHEMBL167103 0.74
SCHEMBL22418799 0.74
SCHEMBL210276 0.74
SCHEMBL5998620 0.74
SCHEMBL2539106 0.72
SCHEMBL16440972 0.72
SCHEMBL9152549 0.72
Hydrochloric Acid SCHEMBL8539702 0.72
SCHEMBL222855 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0773950-B1 LINKED PEPTIDE NUCLEIC ACIDS ISIS PHARMACEUTICALS INC (US) 2007-08-22 EP disclosed
US-20030105286-A1 Linked peptide nucleic acids EGHOLM MICHAEL (US) 2003-06-05 US disclosed
US-6534512-B1 A therapeutic method is provided, employing an antiviral compound of the general formula: nucleosides which exhibit antiviral activity. REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-03-18 US disclosed
US-6441130-B1 FORM TRIPLE STRANDED STRUCTURES WITH NUCLEIC ACIDS ISIS PHARMACEUTICALS, INC. 2002-08-27 US disclosed
US-6072053-A ANTIVIRAL COMPOUND UNIV MINNESOTA (US) 2000-06-06 US disclosed
EP-0773950-A4 LINKED PEPTIDE NUCLEIC ACIDS ISIS PHARMACEUTICALS INC (US) 2000-05-17 EP disclosed
US-5962684-A Method of preparation of dideoxycarbocyclic nucleosides REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-10-05 US disclosed
US-5922694-A SUBSTITUTED-OXY METHYL CYCLOPENTENYL-SUBSTITUTED PURINES AND 8-AZAPURINES ANTI HUMAN IMMUNODEFICIENCY VIRUS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-07-13 US disclosed
EP-0358154-B1 Novel cyclobutane derivative and process for producing same NIPPON KAYAKU KK (JP) 1998-12-02 EP disclosed
EP-0759193-B1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORP (US) 1998-09-09 EP disclosed
US-5175292-A Viricides, aids REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1992-12-29 US disclosed
US-5153352-A Viricides and antitumor agent BRISTOL-MYERS SQUIBB COMPANY (US) 1992-10-06 US disclosed
US-4988703-A Viricides of hydroxyethylcyclopropylguanine ABBOTT LABORATORIES (US) 1991-01-29 US disclosed
US-4950758-A ANTIVIRAL AND ANTITUMOR AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-08-21 US disclosed
US-4931559-A VIRICIDES, ANTITUMOR AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-06-05 US disclosed
WO-1990005730-A2 NOVEL CYCLOBUTANE DERIVATIVE AND PROCESS FOR PRODUCING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-05-31 WO disclosed
EP-0366059-A2 Carbocyclic nucleoside analogs BRISTOL-MYERS SQUIBB COMPANY (US) 1990-05-02 EP disclosed
US-4916224-A VIRICIDES FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-04-10 US disclosed
EP-0358154-A2 Novel cyclobutane derivative and process for producing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-03-14 EP disclosed
EP-0330992-A2 Novel cyclobutane Derivatives, processes for their preparation and pharmaceutical compositions comprising them Nippon Kayaku Kabushiki Kaisha (JP) 1989-09-06 EP disclosed